Next-generation sequencing approaches are rapidly advancing our understanding of pathogens and clinical management of infectious diseases. This collection showcases recent Genome Medicine articles that have made exciting contributions within this field. Articles in this collection cover insights from whole-genome sequencing into pathogen evolution, transmission, and drug resistance, as well as advances in clinical diagnostics of both viral and bacterial pathogens and treatment strategies. Additionally, it features articles focusing on host immune response and protection against infection, from a genomics perspective.
Longitudinal genomic surveillance of multidrug-resistant Escherichia coli carriage in a long-term care facility in the United Kingdom
Residents of long-term care facilities (LTCF) may have high carriage rates of multidrug-resistant pathogens, but are not currently included in surveillance programmes for antimicrobial resistance or healthcare...