BMC Women’s Health welcomed submissions to the Collection Advancing immunotherapy against gynecological cancer.
Gynecological cancer is a kind of tumor identified in the female reproductive organs, including ovarian, cervical, uterine, vaginal, and vulvar cancers, and significantly challenges the health of women worldwide. Immunotherapy represents a promising avenue for the treatment of gynecological cancer by dynamically altering the body's immune system to target and destroy cancer cells in pathways distinct from traditional treatment approaches such as radiotherapy, chemotherapy, surgery, or a combination of these methods. Understanding the interplay between the immune system and various gynecological cancers is crucial for advancing novel therapeutic approaches and improving patient outcomes.
Interventional anti-tumor based immunity has made considerable progress by checkpoint blockade, vaccination and adaptive cellular therapy in certain gynecological cancers. Ongoing research has elucidated the complex tumor microenvironment and immune evasion mechanisms, providing insights into potential targets for immunotherapy. Identification of the nuances of immune-related adverse events and patient selection criteria is essential for optimizing the immunotherapy in gynecological cancers. Further exploration of biomarkers and refined therapy combinations may lead to the development and leverage of personalized immunotherapeutic strategies of gynecological cancers.
Topics welcomed for submission to the Collection included but were not limited to:
- Novel checkpoint inhibitor-based immunotherapy in gynecological cancer
- Research and clinical strategies targeting the tumor microenvironment in gynecological cancer
- Personalized immunotherapeutic strategies for different types of gynecological cancers
- Immune-related adverse events in gynecological cancer patients
- Predictive biomarkers for improving checkpoint blockades
This Collection supports and amplifies research related to SDG 3: Good Health & Well-Being and SDG 5: Gender Equality.
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