In this issue of Genome Biology, we present a special collection of Research, Review, Opinion, Research Highlight and Editorial articles focusing on epigenomics. The issue provides a variety of new insights into the biology of DNA methylation, histone modifications and chromatin organization, and includes perspectives on epigenomics past, present and future from leaders in the field.
The birth of the Epitranscriptome: deciphering the function of RNA modifications
Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-...