Genome Biology is calling for submissions to our Collection on chromatin and epigenomic modifications in development and disease.
Chromatin and epigenomic modifications play essential roles in regulating gene expression and cellular function, which in turn influence developmental processes. Abnormal chromatin changes and epigenomic modifications lead to developmental disorders and progression of diseases. Understanding the mechanisms governing alteration of chromatin and epigenomic modifications is not only crucial for unraveling the complexities of gene expression that impact developmental processes but also important for developing novel diagnostic tools and therapeutic strategies for developmental disorders and diseases.
Recent technological advances allow us to study epigenomic modifications at single nucleotide resolution, to explore three-dimensional chromatin architecture, to decipher epigenetic modification involved transcriptional regulation, and to explore novel epigenetic modifications, providing exciting novel insights into chromatin biology during development and disease.
This collection is calling for submissions on “Chromatin and epigenomic modifications in development and disease”. We aim to advance our understanding of the role and mechanism of chromatin and epigenomics in regulating developmental processes and diseases.
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