Genome Biology is calling for submissions on the collection "Advances in Spatial Transcriptomics for Understanding Development and Disease". This collection aims to highlight recent progress in the field of spatial transcriptomics, with a focus on how the emerging technologies are improving our understanding of the cellular processes and molecular mechanisms underlying developmental processes and disease states.
Spatial transcriptomics is a rapidly evolving field that combines high-throughput sequencing with spatial localization information to generate spatially resolved transcriptome maps of tissues and organs. This approach provides a unique opportunity to study gene expression patterns in their native spatial context, allowing for the identification of novel cell types, signaling pathways, and gene regulatory networks involved in organogenesis, tissue differentiation, and disease processes.
The collection will consider articles showcasing the latest findings in spatial transcriptomics, including but not limited to:
• Methodological advances and development of novel bioinformatic tools for the analysis of spatial transcriptomics data
• Applications of spatial transcriptomics to study the molecular mechanisms underlying normal development and disease states
• Integration of spatial transcriptomics data with other omics datasets, such as proteomics, metabolomics, and epigenomics to enable further insights into a wide range of biological processes
We encourage submissions from a wide range of research areas, including developmental biology, cancer biology, immunology, neuroscience, and computational biology. Articles that incorporate multi-omics approaches or use spatial transcriptomics in combination with other imaging modalities are also welcome.
Please use the online submission system and indicate in your covering letter that you would like the manuscript to be considered for the "Advances in spatial transcriptomics for understanding development and disease" collection. If you would like to inquire about the suitability of a manuscript for consideration, please email a pre-submission inquiry to [email protected].
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